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AI-Backed Biotech Firm Chai Discovery Raises $130M, Valued at $1.3B

AI artificial intelligence biotech venture capital OpenAI Series B drug discovery
December 15, 2025
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Algorithm-Driven Cure
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Article Summary

Chai Discovery, an OpenAI-backed biotech firm, has announced a significant $130 million Series B funding round led by General Catalyst and Oak HC/FT, pushing its total funding to over $225 million. The company is focused on using AI, particularly large language models, to accelerate drug discovery. Chai's core technology revolves around ‘building the “computer aided design suite” for molecules,’ aiming to predict interactions between biochemical molecules and ultimately design custom cures. The latest iteration, Chai 2, demonstrates improved success rates in de novo antibody design compared to traditional methods. Prior to this round, Chai had already released Chai 1, and the company's founder, Josh Meier, brings a strong background in machine learning, having previously worked at Facebook and OpenAI. This substantial investment underscores the growing interest in applying AI to traditionally slow and expensive drug development processes. The funding will be used to expand the team, scale the platform, and continue research efforts, further solidifying Chai Discovery's position within the burgeoning intersection of AI and pharmaceutical innovation.

Key Points

  • Chai Discovery raised $130 million in Series B funding at a $1.3 billion valuation.
  • The investment is fueled by a belief in the potential of AI to revolutionize drug development.
  • Josh Meier, Chai’s CEO, has a background in machine learning, previously working at Facebook and OpenAI.

Why It Matters

This funding round is a critical validation of the growing trend of AI applications in drug discovery. The potential for AI to drastically reduce the time and cost associated with developing new medicines is enormous, offering significant implications for healthcare, pharmaceutical companies, and ultimately, patients. This news demonstrates a shift towards more efficient R&D and highlights the role AI can play in addressing previously intractable medical challenges. This investment also indicates a strong belief in OpenAI’s continued leadership in the field of generative AI.

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